Phytomedicine
Volume 14 , Pages 27-31 , 5 March 2007

Inhibition of lipopolysaccharid-induced sickness behavior by a dry extract from the roots of Pelargonium sidoides (EPs® 7630) in mice

References 

  1. Berg BM, Godbout JP, Kelley KW, Johnson RW. α-Tocopherol attenuates lipopolysaccharide-induced sickness behavior in mice. Brain Behav Immunity. 2004;18:149–157
  2. Castanon N, Bluthe RM, Dantzer R. Chronic treatment with the atypical antidepressant tianeptine attenuates sickness behaviour induced by peripheral but not central lipopolysaccharide and interleukin 1ß in the rat. Psychopharmacology. 2001;154:50–60
  3. Dantzer R. Cytokine-induced sickness behaviour: a neuroimmune response to activation of innate immunity. Eur J Pharmacol. 2004;500:399–411
  4. Kelley KW, Bluthe RM, Dantzer R, Zhou JH, Shen WH, Johnson RW, et al. Cytokine-induced sickness behaviour. Brain Behavior Immunity. 2003;17:S112–S118
  5. Nadjar A, Bluthe RM, May MJ, Dantzer R, Parnet P. Inactivation of the cerebral NFκB pathway inhibits interleukin-1β-induced sickness behavior and c-fos expression in various brain nuclei. Neuropsychopharmacology. 2005;30:1492–1499
  6. Parnet P, Kelley KW, Bluthe RM, Dantzer R. Expression and regulation of interleukin-1 receptors in the brain. Role in cytokines-induced sickness behaviour. J Neuroimmunol. 2002;125:5–14
  7. Schiepers OJG, Wiechers MC, Maes M. Cytokines and major depression. Progr Neuro-Psychopharmacol Biol Psych. 2005;29:201–217
  8. Singal A, Tirkey N, Pilkhwal S, Chopra K. Green tea (Camellia sinensis) extract ameliorates endotoxin induced sickness behavior and liver damage in rats. Phytother Res. 2006;20:125–129
  9. Watanabe S, Kanada S, Takenaka M, Hamazaki T. Dietary n-3 fatty acids selectively attenuates LPS-induced behavioural depression in mice. Physiol Behav. 2004;81:605–613

PII: S0944-7113(06)00188-7

doi: 10.1016/j.phymed.2006.11.013

Phytomedicine
Volume 14 , Pages 27-31 , 5 March 2007

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