Phytomedicine
Volume 14 , Pages 46-51 , 5 March 2007

Extract of Pelargonium sidoides (EPs® 7630) improves phagocytosis, oxidative burst, and intracellular killing of human peripheral blood phagocytes in vitro

References 

  1. Anding K, Rost JM, Jacobs E, Daschner FD. Flow cytometric measurements of neutrophil functions: the dependence on the stimulus to cell ratio. FEMS Immunol. Med. Microbiol. 2003;35:147–152
  2. Bereznoy VV, Riley DS, Wassmer G, Heger M. Efficiacy of extract of Pelargonium sidoides in children with acute non-group A beta-hemolytic streptococcus tonsillopharyngitis: a randomized, double-blind, placebo-controlled trial. Altern. Ther. Health Med. 2003;9:68–78
  3. Frank U, Engels I, Wagner A, Lacour M, Daschner FD. Influence of mistletoe (Viscum album) extracts on phagocytosis/burst activity of human phagocytes. Eur. J. Clin. Microbiol. Infect. Dis. 2003;22:501–503
  4. Greenberg S, Grinstein S. Phagocytosis and innate immunity. Curr. Opin. Immunol. 2002;14:136–145
  5. Henneke P, Golenbock DT. Phagocytosis, innate immunity, and host–pathogen specifity. J. Exp. Med. 2004;199:1–4
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  7. Kayser O, Kolodziej H. Antibacterial activity of extracts and constituents of Pelargonium sidoides and Pelargonium reniforme. Planta Med. 1997;63:508–510
  8. Kayser O, Kolodziej H, Kiderlen F. Immunomodulatory principles of Pelargonium sidoides. Phytother. Res. 2001;15:122–126
  9. Kobayashi SD, Voyich JM, Burlak C, DeLeo FR. Neutrophils in the immune response. Arch. Immunol. Ther. Exp. (Warsz). 2005;53:505–517
  10. Kolodziej H, Kayser O, Radtke OA, Kiderlen AF, Koch E. Pharmacological profile of extracts of Pelargonium sidoides and their constituents. Phytomedicine. 2003;10:18–24
  11. Matthys H, Eisebitt R, Seith B, Heger M. Efficiacy and safety of an extract of Pelargonium sidoides (EPs 7630) in adults with acute bronchitis. A randomized, double-blind, placebo-controlled trial. Phytomedicine. 2003;10:7–17
  12. Neugebauer P, Mickenhagen A, Siefer O, Walger M. A new approach to pharmacological effects on ciliary beat frequency in cell cultures – exemplary measurements under Pelargonium sidoides extract (EPs 7630). Phytomedicine. 2005;12:47–52
  13. Salih HR, Husfeld L, Adam D. Simultaneous cytofluorometric measurement of phagocytosis, burst production and killing of human phagocytes using Candida albicans and Staphylococcus aureus as target organisms. Clin. Microbiol. Infect. 2000;6:251–258

PII: S0944-7113(06)00191-7

doi: 10.1016/j.phymed.2006.11.016

Phytomedicine
Volume 14 , Pages 46-51 , 5 March 2007

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