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Phytomedicine
Volume 14
, Pages 40-45
, 5 March 2007
Treatment of rats with the Pelargonium sidoides extract EPs® 7630 has no effect on blood coagulation parameters or on the pharmacokinetics of warfarin
References
- . Was ist dran an Umckaloabo?. Arznei-Telegramm. 2003;34:28–29
- . Determining the best animal model for human cytochrome P450 activities: a comparison of mouse, rat, rabbit, dog, micropig, monkey and man. Xenobiotica. 2000;30:1131–1152
- . Human P450 metabolism of warfarin. Pharmacol. Ther. 1997;73:67–74
- . Umckaloabo. Dts. Apoth. Ztg. 2003;143:55–64
- . Pharmacological profile of extracts of Pelargonium sidoides and their constituents. Phytomedicine. 2003;10(Suppl. IV):18–24
- . Unusual coumarin pattern of Pelargonium species forming the origin of the traditional herbal medicine Umckaloabo. Z. Naturforsch. 2000;55c:528–533
- . Anticoagulant, thrombolytic, and antiplatelet drugs. In: Hardman JG, Limbird LE editor. Goodman & Gilman's The Pharmacological Basis of Therapeutics. 10th ed. New York: McGraw-Hill; 2001;p. 1519–1538
- . Aspects of anticoagulant action: a review of the pharmacology, metabolism and toxicology of warfarin and congeners. Drug Metabol. Drug Interact. 1987;5:225–272
- . Coumarin derivatives (rodenticides). Toxicology. 1994;91:71–76
- Wittkowsky A., 2002. Warfarin and its potential interactions with traditional drugs and botanical agents. 〈http://www.pshp.org/ce_files/adis_anticoag.html〉. Accessed on 24.10.2003.
- . Über die gerinnungshemmende Wirkung der Umckaloabo®-Droge. Ärztl. Forsch. 1965;19:278–280
PII: S0944-7113(06)00201-7
doi: 10.1016/j.phymed.2006.11.026
© 2006 Elsevier GmbH. All rights reserved.
« Previous
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Phytomedicine
Volume 14
, Pages 40-45
, 5 March 2007
