Phytomedicine
Volume 16, Issue 2 , Pages 215-221 , March 2009

Chinese medicinal formula Guan-Xin-Er-Hao protects the heart against oxidative stress induced by acute ischemic myocardial injury in rats

  • F. Qin

      Affiliations

    • Laboratory of Ethnopharmacology and Institute of Integrated Chinese and Western Medicine, Xiangya Hospital, Central South University, Changsha 410008, PR China
    • ,
  • Y.-X. Liu

      Affiliations

    • Department of Integrated Chinese and Western Medicine, West China Hospital, Sichuan University, Chengdu 610041, PR China
    • ,
  • H.-W. Zhao

      Affiliations

    • Department of Integrated Chinese and Western Medicine, West China Hospital, Sichuan University, Chengdu 610041, PR China
    • ,
  • X. Huang

      Affiliations

    • Laboratory of Ethnopharmacology and Institute of Integrated Chinese and Western Medicine, Xiangya Hospital, Central South University, Changsha 410008, PR China
    • Corresponding Author InformationCorresponding author. Tel.: +867314327222; fax: +867314328386.
    • ,
  • P. Ren

      Affiliations

    • Laboratory of Ethnopharmacology and Institute of Integrated Chinese and Western Medicine, Xiangya Hospital, Central South University, Changsha 410008, PR China
    • ,
  • Z.-Y. Zhu

      Affiliations

    • Department of Integrated Chinese and Western Medicine, West China Hospital, Sichuan University, Chengdu 610041, PR China

References 

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  18. Shidoji Y, Okamoto K, Muto Y, Komura S, Ohishi N, Yagi K. Prevention of geranylgeranoic acid-induced apoptosis by phospholipid hydroperoxide glutathione peroxidase gene. J. Cell. Biochem. 2006;97:178–187
  19. Wang ZY, Qian RQ, Guan SH. Study on free radical mechanism of guanxin II in antagonizing ischemic myocardial damage. Chin. J. Integ. Trad. West Med. 2003;23:363–366
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  22. Xu R, Huang X, Li Y, Zhang L, Wang L, Cui P. Clinical observation of treating coronary heart disease with Guanxin-erhao. J. Chengdu Univ. TCM. 2001;24:17–19
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  24. Zhao J, Huang X, Tang W, Ren P, Xing Z, Tian X, et al. Effect of oriental herbal prescription Guan-Xin-Er-Hao on coronary flow in healthy volunteers and anti-apoptosis on myocardial ischemia-reperfusion in rat models. Phytother. Res. 2007;21:926–931
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  27. Zhu AM, Huo P. Treating 42 cases of senile coronary heart disease with Guanxin – II prescription. Hunan Guiding J. TCMP. 2002;8:63

PII: S0944-7113(08)00161-X

doi: 10.1016/j.phymed.2008.08.005

Phytomedicine
Volume 16, Issue 2 , Pages 215-221 , March 2009

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