Phytomedicine
Volume 17, Issue 10 , Pages 782-788, August 2010

Pisiferdiol and pisiferic acid isolated from Chamaecyparis pisifera activate protein phosphatase 2C in vitro and induce caspase-3/7-dependent apoptosis via dephosphorylation of Bad in HL60 cells

  • N. Aburai

      Affiliations

    • Laboratory of Chemical Biology, The United Graduate School of Agricultural Sciences, Iwate University, Morioka, Iwate 020-8550, Japan
  • ,
  • M. Yoshida

      Affiliations

    • Graduate School of Bioscience and Biotechnology, Chubu University, Kasugai, Nagoya 487-8501, Japan
  • ,
  • M. Ohnishi

      Affiliations

    • Graduate School of Bioscience and Biotechnology, Chubu University, Kasugai, Nagoya 487-8501, Japan
  • ,
  • K. Kimura

      Affiliations

    • Laboratory of Chemical Biology, The United Graduate School of Agricultural Sciences, Iwate University, Morioka, Iwate 020-8550, Japan
    • Corresponding Author InformationCorresponding author at: Department of Biological Chemistry and Food Science, 3-18-8 Ueda, Morioka 020-8550, Japan. Tel./fax: +81196216124.

published online 15 February 2010.

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PII: S0944-7113(09)00347-X

doi:10.1016/j.phymed.2009.12.015

Phytomedicine
Volume 17, Issue 10 , Pages 782-788, August 2010